The Rare Disease Legislative Caucus is a bipartisan congressional caucus open to all members of the United States House and Senate. The caucus is currently co-chaired by Representatives G.K. Butterfield (D-NC) and Gus Bilirakis (R-FL) and Senators Roger Wicker (R-MS) and Amy Klobuchar (D-MN). The caucus was founded and Chaired by Congressman Fred Upton (R-MI) and Joseph Crowley in 2009.