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Red ear syndrome (RES) is a rare disorder of unknown etiology which was originally described in 1994. The defining symptom of red ear syndrome is redness of one or both external ears, accompanied by a burning sensation. A variety of treatments have been tried with limited success.

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  • متلازمة الأذن الحمراء (ar)
  • Syndrome de l'oreille rouge (fr)
  • Sindrome dell'orecchio rosso (it)
  • Red ear syndrome (en)
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  • متلازمة الأذن الحمراء (بالإنجليزية: Red Ear Syndrome) هي خلل نادر لسبب غير معلوم وصفت لأول مرة في 1994. العرض الرئيسي لمتلازمة الأذن الحمراء هو احمرار إحدى أو كلا الأذنين من الخارج، مصحوبة بشعور بالحرقة. تمت تجربة العديد من العلاجات ولكنها لاقت نجاحًا محدودًا. (ar)
  • Red ear syndrome (RES) is a rare disorder of unknown etiology which was originally described in 1994. The defining symptom of red ear syndrome is redness of one or both external ears, accompanied by a burning sensation. A variety of treatments have been tried with limited success. (en)
  • Le syndrome de l'oreille rouge est une maladie rare, d'étiologie inconnue, qui fut décrite pour la première fois en 1994. Le symptôme-clé de ce syndrome est l'érythème de l'une ou des deux oreilles externes, accompagné d'une sensation de brûlure. Divers traitements ont été proposés avec une efficacité limitée. (fr)
  • La sindrome dell'orecchio rosso o eritromelalgia auricolare è una rara sindrome dolorosa che può colpire uno dei due orecchi dell'uomo, più raramente entrambi.Venne per la prima volta descritta nel 1996 da Lance.La possibilità di contrarre la sindrome è circa dello 0,0000012% e precisamente non è ancora nota la precisa causa della sindrome stessa. Il tasso di morte procurato dalla sindrome è per niente elevato, si contano infatti solo pochi decessi, 20 in tutto, probabilmente legati alla sindrome negli Stati Uniti. Non esiste un vero studio clinico ma ne sono stati effettuati alcuni negli Stati Uniti di cui alcuni ancora in corso e alcuni in Canada. (it)
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  • A red ear syndrome attack, with affected ear on the left (en)
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  • متلازمة الأذن الحمراء (بالإنجليزية: Red Ear Syndrome) هي خلل نادر لسبب غير معلوم وصفت لأول مرة في 1994. العرض الرئيسي لمتلازمة الأذن الحمراء هو احمرار إحدى أو كلا الأذنين من الخارج، مصحوبة بشعور بالحرقة. تمت تجربة العديد من العلاجات ولكنها لاقت نجاحًا محدودًا. تعد الأذن الحمراء أيضًا عرض تقليديلالتهاب الغضاريف الناكس، مرض مناعي نادر يهاجم مناطق غضروفية متنوعة في الجسم (وأحيانا مناطق أنسجة ضامة أخرى)، تقدر الأبحاث أن التهاب الغضاريف الناكس يصيب 3-5 أشخاص لكل مليون شخص. تشير الأذن الحمراء في حالة التهاب الغضاريف الناكس إلى التهاب في الغضروف (وأحيانًا التهاب الجلد الخارجي للأذن إلى جانب الغضروف) وتتسبب غالبا في ألم متوسط إلى شديد خلال «توهجات» المرض، والتي قد تكون حادة أو مزمنة. قد تتضمن الأذن الحمراء في التهاب الغضاريف الناكس أذنًا واحدة أو كلتا الأذنين، وتوصف بـ«ادخار شحمة الأذن» نتيجة غياب الغضروف في شحمة الأذن. قد يتسبب الالتهاب لفترات طويلة في تدهور غضروف الأذن (توصف عادة بـ«أذن قرنبيطية» أو «أذن مرنة»)، وقد يؤدي حتى إلى فقد جزئي أو كلي للسمع. (ar)
  • Red ear syndrome (RES) is a rare disorder of unknown etiology which was originally described in 1994. The defining symptom of red ear syndrome is redness of one or both external ears, accompanied by a burning sensation. A variety of treatments have been tried with limited success. Red ears are also often a classic symptom of relapsing polychondritis (RP), a rare autoimmune disease that attacks various cartilage areas (and sometimes other connective tissue areas) in the body; research estimates that RP affects 3-5 people per million. Red ears in RP indicate inflamed cartilage (and sometimes the skin of the outer ear along with the cartilage) and often cause moderate to extreme pain during “flares” of the disease, which can be acute and/or chronic. Red ears in RP can be bilateral or unilateral, and are described as “earlobe sparing” due to the lack of cartilage in the earlobe. Prolonged inflammation can eventually result in deteriorated ear cartilage (often described as “cauliflower ear” or “floppy ear”), and even partial or total loss of hearing. (en)
  • Le syndrome de l'oreille rouge est une maladie rare, d'étiologie inconnue, qui fut décrite pour la première fois en 1994. Le symptôme-clé de ce syndrome est l'érythème de l'une ou des deux oreilles externes, accompagné d'une sensation de brûlure. Divers traitements ont été proposés avec une efficacité limitée. L'érythème des oreilles est également un symptôme classique de la polychondrite atrophiante (PCA), une maladie auto-immune rare qui touche différentes zones de cartilage (et parfois d'autres zones de tissus conjonctifs) du corps ; on estime que la PCA touche 3 à 5 personnes par million d'habitants. L'érythème des oreilles dans la PCA est un signe d'inflammation du cartilage (et parfois de la peau de l'oreille externe en plus du cartilage) et cause souvent des douleurs modérées à importantes lors des “poussées” de la maladie, qui peut être aiguë et/ou chronique. L'érythème des oreilles dans la PCA peut être unilatéral ou bilatéral. Une inflammation prolongée peut entraîner une détérioration du cartilage de l'oreille (souvent décrite comme “oreille en chou-fleur”), voire une perte partielle ou totale de l'audition. (fr)
  • La sindrome dell'orecchio rosso o eritromelalgia auricolare è una rara sindrome dolorosa che può colpire uno dei due orecchi dell'uomo, più raramente entrambi.Venne per la prima volta descritta nel 1996 da Lance.La possibilità di contrarre la sindrome è circa dello 0,0000012% e precisamente non è ancora nota la precisa causa della sindrome stessa. Il tasso di morte procurato dalla sindrome è per niente elevato, si contano infatti solo pochi decessi, 20 in tutto, probabilmente legati alla sindrome negli Stati Uniti. Non esiste un vero studio clinico ma ne sono stati effettuati alcuni negli Stati Uniti di cui alcuni ancora in corso e alcuni in Canada. In letteratura scientifica sono descritti ad oggi circa 102 pazienti, di cui alcuni casi negli Stati Uniti che hanno provocato il decesso dei pazienti,i casi sono in rapporto tra maschi e femmine di 1:1,25 con un'età media di esordio di 44 anni, con una vasta gamma di età di esordio: da 4 a 92 anni. Dei 101 pazienti noti solamente 4 finora erano afflitti dalla sindrome da ambedue i lati, di cui solo uno europeo, più precisamente in Italia. La maggior parte dei casi noti finora si sono verificati negli Stati Uniti, ben 89. In Europa sono stati solamente 6 i casi e si sono verificati in Francia,Germania, Spagna ed 1 in Italia I restanti 7 casi si sono verificati in Canada. (it)
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