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About: Reversine     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:WikicatPurines, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substanceChemical compoundyago:WikicatAnilinesyago:WikicatAromaticAminesyago:Abstraction100002137yago:AliphaticCompound114601294yago:Amine114739004yago:Aniline114754505yago:Base114618253yago:Chemical114806838yago:Compound114818238yago:Material114580897yago:Matter100020827yago:MethaneSeries114951377yago:OrganicCompound114727670yago:Part113809207yago:PhysicalEntity100001930yago:Purine114706749yago:Relation100031921chemical compoundyago:Substance100019613yago:WikicatPurines New Facet based on Instances of this Class

Reversine, or 2-(4-morpholinoanilino)-6-cyclohexylaminopurine, is a small molecule developed by the group of Peter G. Schultz, used for stem cell dedifferentiation. It also has the potential to selectively induce cell death in cancer cells. Reversine is known to act as an antagonist of the adenosine A3 receptor. Reversine is a potent inhibitor of the mitotic kinase Mps1 and it is widely used to study the process of chromosome segregation.