About: Ritalinic acid     Goto   Sponge   NotDistinct   Permalink

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Ritalinic acid is a substituted phenethylamine and an inactive major metabolite of the psychostimulant drugs methylphenidate and ethylphenidate. When administered orally, methylphenidate is extensively metabolized in the liver by hydrolysis of the ester group yielding ritalinic acid. The hydrolysis was found to be catalyzed by carboxylesterase 1 (CES1). Etymologically, ritalinic acid shares its roots with Ritalin, a common brand name for methylphenidate.

AttributesValues
rdf:type
rdfs:label
  • Ritalinic acid (en)
  • Ácido ritalínico (pt)
rdfs:comment
  • Ritalinic acid is a substituted phenethylamine and an inactive major metabolite of the psychostimulant drugs methylphenidate and ethylphenidate. When administered orally, methylphenidate is extensively metabolized in the liver by hydrolysis of the ester group yielding ritalinic acid. The hydrolysis was found to be catalyzed by carboxylesterase 1 (CES1). Etymologically, ritalinic acid shares its roots with Ritalin, a common brand name for methylphenidate. (en)
  • Ácido ritalínico é uma fenetilamina substituída e um dos principais metabólitos inativos das drogas psicoestimulantes metilfenidato e etilfenidato. Quando administrado por via oral, o metilfenidato é extensamente metabolizado no fígado por hidrólise do grupo éster, originando o ácido ritalínico. A hidrólise é catalisada pela enzima carboxilesterase 1 (CES1). (pt)
foaf:depiction
  • http://commons.wikimedia.org/wiki/Special:FilePath/Ritalinic_acid-2D-skeletal.svg
dcterms:subject
Wikipage page ID
Wikipage revision ID
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Link from a Wikipage to an external page
sameAs
dbp:wikiPageUsesTemplate
thumbnail
ATC prefix
  • None (en)
c
CAS number
ChemSpiderID
H
IUPAC name
  • Phenylacetic acid (en)
legal US
  • Unscheduled and Uncontrolled (en)
n
O
PubChem
SMILES
  • C1CCNCCCO (en)
StdInChI
  • InChI=1S/C13H17NO2/c15-131211-8-4-5-9-14-11/h1-3,6-7,11-12,14H,4-5,8-9H2, (en)
StdInChIKey
  • INGSNVSERUZOAK-UHFFFAOYSA-N (en)
UNII
  • GT4165RS9H (en)
verifiedrevid
Watchedfields
  • changed (en)
has abstract
  • Ritalinic acid is a substituted phenethylamine and an inactive major metabolite of the psychostimulant drugs methylphenidate and ethylphenidate. When administered orally, methylphenidate is extensively metabolized in the liver by hydrolysis of the ester group yielding ritalinic acid. The hydrolysis was found to be catalyzed by carboxylesterase 1 (CES1). Etymologically, ritalinic acid shares its roots with Ritalin, a common brand name for methylphenidate. (en)
  • Ácido ritalínico é uma fenetilamina substituída e um dos principais metabólitos inativos das drogas psicoestimulantes metilfenidato e etilfenidato. Quando administrado por via oral, o metilfenidato é extensamente metabolizado no fígado por hidrólise do grupo éster, originando o ácido ritalínico. A hidrólise é catalisada pela enzima carboxilesterase 1 (CES1). (pt)
gold:hypernym
prov:wasDerivedFrom
page length (characters) of wiki page
CAS number
  • 19395-41-6
FDA UNII code
  • GT4165RS9H
PubChem
  • 86863
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