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Rubratoxins are hepatotoxic mycotoxin produced by Penicillium rubrum and Penicillium purpurogenum. Rubratoxin A and rubratoxin B have been known since 1950s, while rubratoxin C was recently reported. Rubratoxins are also known as protein phosphatase 2A (PP2A) specific inhibitor. The PP2A inhibitory activity of rubratoxin A is about 100-fold higher than rubratoxin B and rubratoxin A is now used as a chemical probe for PP2A research. * Rubratoxin A * Rubratoxin B * Rubratoxin C

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  • ルブラトキシン (ja)
  • Rubratoxin (en)
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  • Rubratoxins are hepatotoxic mycotoxin produced by Penicillium rubrum and Penicillium purpurogenum. Rubratoxin A and rubratoxin B have been known since 1950s, while rubratoxin C was recently reported. Rubratoxins are also known as protein phosphatase 2A (PP2A) specific inhibitor. The PP2A inhibitory activity of rubratoxin A is about 100-fold higher than rubratoxin B and rubratoxin A is now used as a chemical probe for PP2A research. * Rubratoxin A * Rubratoxin B * Rubratoxin C (en)
  • ルブラトキシン (rubratoxin) は Penicillium rubrum および Penicillium purpurogenum により産生されるマイコトキシンの一種であり、哺乳類に対して肝毒性を示すことが知られている。古くからルブラトキシンAとBが知られていたが、2014年、Penicillium属の未記載種からのルブラトキシンCの単離が報告された 。ルブラトキシンはプロテインホスファターゼ2A (PP2A) の特異的な阻害剤としても知られ、特にルブラトキシンAのPP2A阻害活性はBに比べて100倍ほど強力であり、現在は研究試薬として用いられている 。 * ルブラトキシンA * ルブラトキシンB * ルブラトキシンC (ja)
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  • http://commons.wikimedia.org/wiki/Special:FilePath/Rubratoxin_A.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/Rubratoxin_B_revised.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/Rubratoxin_C.png
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  • Rubratoxins are hepatotoxic mycotoxin produced by Penicillium rubrum and Penicillium purpurogenum. Rubratoxin A and rubratoxin B have been known since 1950s, while rubratoxin C was recently reported. Rubratoxins are also known as protein phosphatase 2A (PP2A) specific inhibitor. The PP2A inhibitory activity of rubratoxin A is about 100-fold higher than rubratoxin B and rubratoxin A is now used as a chemical probe for PP2A research. * Rubratoxin A * Rubratoxin B * Rubratoxin C (en)
  • ルブラトキシン (rubratoxin) は Penicillium rubrum および Penicillium purpurogenum により産生されるマイコトキシンの一種であり、哺乳類に対して肝毒性を示すことが知られている。古くからルブラトキシンAとBが知られていたが、2014年、Penicillium属の未記載種からのルブラトキシンCの単離が報告された 。ルブラトキシンはプロテインホスファターゼ2A (PP2A) の特異的な阻害剤としても知られ、特にルブラトキシンAのPP2A阻害活性はBに比べて100倍ほど強力であり、現在は研究試薬として用いられている 。 * ルブラトキシンA * ルブラトキシンB * ルブラトキシンC (ja)
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