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About: Run-in period     Goto   Sponge   NotDistinct   Permalink

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Run-in period is a period between the recruitment and randomization phases of a clinical trial, when all participants receive the same treatment, which may be active treatment, a placebo or no treatment at all. The from this stage of a trial are only occasionally of value but can serve a valuable role in screening out ineligible or non-compliant participants, in ensuring that participants are in a stable condition, and in providing baseline observations. A run-in period is sometimes called a washout period if treatments that participants were using before entering the clinical trial are discontinued.