SRG1 RNA (SER3 regulatory gene 1) is a non-coding RNA which represses the expression of SER3 (YER081W). SER3 is a gene which codes for a phosphoglycerate dehydrogenase involved in the biosynthesis of serine. SRG1 represses SER3 expression via transcription interference, and in that respect is the first intergenic transcript of its kind. SRG1 RNA is unrelated to Senescence Related Gene 1 (SRG1), a protein-coding gene found in Arabidopsis thaliana, and is also distinct from Stress Response Gene 1 (SRG1) found in Medicago sativa.
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