Sanghamitra Bandyopadhyay (born 1968) is an Indian computer scientist specializing in computational biology. A professor at the Indian Statistical Institute, Kolkata, she is a Shanti Swarup Bhatnagar Prize winner in Engineering Science for 2010, IInfosys Prize 2017 laureate in the Engineering and Computer Science category and TWAS Prize winner for Engineering Sciences in 2018 Her research is mainly in the areas of evolutionary computation, pattern recognition, machine learning and bioinformatics. Since 1 August 2015, she has been the Director of the Indian Statistical Institute, and she would oversee the functioning of all five centres of Indian Statistical Institute located at Kolkata, Bangalore, Delhi, Chennai, and Tezpur besides several other Statistical Quality Control & Operation Res