Highway 48 is a highway in the Canadian province of Saskatchewan. It runs from Highway 1 at White City, about 10 km (6 mi) east of Regina, to the Manitoba–Saskatchewan border, where it becomes Provincial Road 257. Highway 48 is about 238 km (148 mi) long. This highway was known as Saskatchewan Highway 16 until 1976. It was renumbered as Highway 48 when the Yellowhead Highway was designated as Highway 16 throughout the province.