About: Serdexmethylphenidate

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Serdexmethylphenidate (SDX) is a prodrug of dexmethylphenidate created by the pharmaceutical company KemPharm. The compound was first approved by the FDA as one of the active ingredients in Azstarys for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in children, adolescents, and adults in March 2021. SDX is a prodrug which has a delayed onset of action and a prolonged duration of effects compared to dexmethylphenidate, its parent compound.

Attributes	Values
rdf:type	Thing dul:ChemicalObject chemical substance Drug drug
rdfs:label	Serdexmethylphenidat (de) Serdexmethylphenidate (en) Serdexmetilfenidato (pt)
rdfs:comment	Serdexmethylphenidat ist ein Arzneistoff aus der Gruppe der Stimulantien. Es wird in fester Kombination mit Dexmethylphenidat in der oralen Behandlung der Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung (ADHS) bei Patienten im Alter von sechs Jahren und älter eingesetzt. (de) Serdexmethylphenidate (SDX) is a prodrug of dexmethylphenidate created by the pharmaceutical company KemPharm. The compound was first approved by the FDA as one of the active ingredients in Azstarys for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in children, adolescents, and adults in March 2021. SDX is a prodrug which has a delayed onset of action and a prolonged duration of effects compared to dexmethylphenidate, its parent compound. (en) O serdexmetilfenidato (SDX) é um pró-fármaco do desmetilfenidato, desenvolvido pela farmacêutica americana KemPharm. Em 2021, o composto foi aprovado nos Estados Unidos como um dos princípios ativos do Azstarys, uma associação medicamentosa usada no tratamento do transtorno do déficit de atenção e hiperatividade (TDAH) em crianças, adolescentes e adultos. Comparado ao desmetilfenidato, composto do qual o serdexmetilfenidato é derivado, o SDX apresenta um início de ação retardado e seus efeitos possuem uma duração mais prolongada. (pt)
differentFrom	Dexmethylphenidate Serdexmethylphenidate
foaf:depiction
dcterms:subject	Pyridinium compounds Stimulants Nootropics Norepinephrine–dopamine reuptake inhibitors 2-Benzylpiperidines Methylphenidate
Wikipage page ID	65848960 (xsd:integer)
Wikipage revision ID	1097171032 (xsd:integer)
Link from a Wikipage to another Wikipage	Azstarys Onset of action Ritalinic acid Insufflation (medicine) Pyridinium compounds Stimulants Controlled Substances Act Oral administration Substance use disorder Prodrug Stimulant Nootropics Norepinephrine–dopamine reuptake inhibitors Drug Enforcement Administration Food and Drug Administration List of Schedule IV drugs (US) 2-Benzylpiperidines Methylphenidate Attention deficit hyperactivity disorder Dexmethylphenidate Serdexmethylphenidate/dexmethylphenidate CNS disorders Sleep disorder Stimulant use disorder U.S. Department of Health and Human Services
Link from a Wikipage to an external page	https://druginfo.nlm.nih.gov/drugportal/name/serdexmethylphenidate
sameAs	Serdexmethylphenidate Serdexmethylphenidate Serdexmethylphenidate Serdexmethylphenidate
dbp:wikiPageUsesTemplate	dbt:Cite_web dbt:Distinguish dbt:Infobox_drug dbt:Nervous-system-drug-stub dbt:Portal_bar dbt:Reflist dbt:Short_description dbt:Cascite dbt:ADHD_pharmacotherapies dbt:Monoamine_reuptake_modulators
thumbnail	wiki-commons:Special:FilePath/Serdexmethylphenidate_2D_Structure.svg?width=300
alt	Skeletal formula of serdexmethylphenidate (en)
ATC prefix	None (en)
bioavailability	< 3% (en)
c	25 (xsd:integer)
CAS number	1996626 (xsd:integer)
ChEMBL	4298139 (xsd:integer)
ChemSpiderID	81368035 (xsd:integer)
Cl	1 (xsd:integer)
H	30 (xsd:integer)
IUPAC name	-L-serinate chloride (en)
KEGG	D11401 (en)
legal status	Rx-only (en)
legal US	Schedule IV (en)
n	3 (xsd:integer)
O	8 (xsd:integer)
PubChem	134823897 (xsd:integer)
routes of administration	Oral administration
SMILES	COC[C@@H]C3=CC=CC=C3.[Cl-] (en)
StdInChI	1 (xsd:integer)
StdInChIKey	GONQEUJYYMYNMN-HWAJWLCKSA-N (en)
synonyms	SDX (en)
UNII	FN54BT298Y (en)
verifiedrevid	448081332 (xsd:integer)
Watchedfields	changed (en)
width	250 (xsd:integer)
has abstract	Serdexmethylphenidat ist ein Arzneistoff aus der Gruppe der Stimulantien. Es wird in fester Kombination mit Dexmethylphenidat in der oralen Behandlung der Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung (ADHS) bei Patienten im Alter von sechs Jahren und älter eingesetzt. (de) Serdexmethylphenidate (SDX) is a prodrug of dexmethylphenidate created by the pharmaceutical company KemPharm. The compound was first approved by the FDA as one of the active ingredients in Azstarys for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in children, adolescents, and adults in March 2021. SDX is a prodrug which has a delayed onset of action and a prolonged duration of effects compared to dexmethylphenidate, its parent compound. (en) O serdexmetilfenidato (SDX) é um pró-fármaco do desmetilfenidato, desenvolvido pela farmacêutica americana KemPharm. Em 2021, o composto foi aprovado nos Estados Unidos como um dos princípios ativos do Azstarys, uma associação medicamentosa usada no tratamento do transtorno do déficit de atenção e hiperatividade (TDAH) em crianças, adolescentes e adultos. Comparado ao desmetilfenidato, composto do qual o serdexmetilfenidato é derivado, o SDX apresenta um início de ação retardado e seus efeitos possuem uma duração mais prolongada. (pt)
DailyMedID	Serdexmethylphenidate (en)
metabolites	Ritalinic acid Dexmethylphenidate
prov:wasDerivedFrom	wikipedia-en:Serdexmethylphenidate?oldid=1097171032&ns=0
page length (characters) of wiki page	9004 (xsd:nonNegativeInteger)
CAS number	1996626-30-2
ChEMBL	4298139
FDA UNII code	FN54BT298Y
KEGG	D11401

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