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A sessile serrated lesion (SSL) is a premalignant flat (or sessile) lesion of the colon, predominantly seen in the cecum and ascending colon. SSLs are thought to lead to colorectal cancer through the (alternate) serrated pathway. This differs from most colorectal cancer, which arises from mutations starting with inactivation of the APC gene. Multiple SSLs may be part of the serrated polyposis syndrome.

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  • ورم حميد مسنن (ar)
  • Adénome festonné sessile (fr)
  • Sessile serrated lesion (en)
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  • الورم الحميد المسنن (SSA) هو ما قبل سرطان مسطحة (أو لاطئة) آفة من القولون، وينظر في الغالب في الأعور والقولون الصاعد. ويعتقد أن SSAs يؤدي إلى سرطان القولون والمستقيم من خلال المسار المسنن (البديل). هذا يختلف عن معظم سرطان القولون والمستقيم، والذي ينشأ من الطفرات التي تبدأ مع تعطيل الجين (APC). (ar)
  • A sessile serrated lesion (SSL) is a premalignant flat (or sessile) lesion of the colon, predominantly seen in the cecum and ascending colon. SSLs are thought to lead to colorectal cancer through the (alternate) serrated pathway. This differs from most colorectal cancer, which arises from mutations starting with inactivation of the APC gene. Multiple SSLs may be part of the serrated polyposis syndrome. (en)
  • L'adénome festonné sessile (AFS) est un sous-type d'adénome colorectal et de polype festonné colorectal. Il constitue une lésion précurseur de l'adénocarcinome colorectal. Ils siègent principalement dans le côlon droit. Ils se présentent comme des lésions planes ou légèrement en relief, souvent étendues et parfois multiples, correspondant alors aux lésions de la . Cette lésion s'associe à des mutations de qui laisse penser que ces lésions pourraient être un stade précoce du processus conduisant à l'émergence des cancers coliques sporadiques de phénotype "microsatellite instable" (MSI). (fr)
foaf:name
  • Sessile serrated lesion (en)
name
  • Sessile serrated lesion (en)
foaf:depiction
  • http://commons.wikimedia.org/wiki/Special:FilePath/Sessile_serrated_adenoma_2_high_mag.jpg
  • http://commons.wikimedia.org/wiki/Special:FilePath/Sessile_serrated_adenoma_3_intermed_mag.jpg
  • http://commons.wikimedia.org/wiki/Special:FilePath/Sessile_serrated_adenoma_3_low_mag.jpg
  • http://commons.wikimedia.org/wiki/Special:FilePath/Sessile_serrated_adenoma_3_very_high_mag.jpg
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diagnosis
symptoms
  • Asymptomatic (en)
treatment
caption
  • Micrograph of a sessile serrated lesion. H&E stain. (en)
field
synonyms
  • Sessile serrated adenoma (en)
  • Sessile serrated polyp (en)
has abstract
  • الورم الحميد المسنن (SSA) هو ما قبل سرطان مسطحة (أو لاطئة) آفة من القولون، وينظر في الغالب في الأعور والقولون الصاعد. ويعتقد أن SSAs يؤدي إلى سرطان القولون والمستقيم من خلال المسار المسنن (البديل). هذا يختلف عن معظم سرطان القولون والمستقيم، والذي ينشأ من الطفرات التي تبدأ مع تعطيل الجين (APC). (ar)
  • A sessile serrated lesion (SSL) is a premalignant flat (or sessile) lesion of the colon, predominantly seen in the cecum and ascending colon. SSLs are thought to lead to colorectal cancer through the (alternate) serrated pathway. This differs from most colorectal cancer, which arises from mutations starting with inactivation of the APC gene. Multiple SSLs may be part of the serrated polyposis syndrome. (en)
  • L'adénome festonné sessile (AFS) est un sous-type d'adénome colorectal et de polype festonné colorectal. Il constitue une lésion précurseur de l'adénocarcinome colorectal. Ils siègent principalement dans le côlon droit. Ils se présentent comme des lésions planes ou légèrement en relief, souvent étendues et parfois multiples, correspondant alors aux lésions de la . Cette lésion s'associe à des mutations de qui laisse penser que ces lésions pourraient être un stade précoce du processus conduisant à l'émergence des cancers coliques sporadiques de phénotype "microsatellite instable" (MSI). (fr)
complications
treatment
complications
  • Colorectal cancer
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