Sherburne High School is a historic high school located at Sherburne in Chenango County, New York. It was constructed in two phases, 1924–1925, and 1935. The building ceased being used as a school in 1981 after consolidation in the Sherburne-Earlville Central School in 1971 and subsequent use as an intermediate school. It was added to the National Register of Historic Places in 1988.