Sir Frederick Fletcher-Vane, 2nd Baronet (27 February 1760 – 26 February 1832), was a British politician, landowner and aristocrat. He was MP for the pocket borough of Winchelsea, between 1792 and 1794, the borough of Carlisle, between 1796 and 1802, and again for Winchelsea, between 1806 and 1807. Sir Frederick was the 2nd Baronet of Hutton and a descendant of Sir Henry Vane the Elder. In 1788 he served as High Sheriff of Cumberland.