Sofija Smetonienė (née Chodakauskaitė; January 13, 1885 – December 28, 1968), was the wife of the first President of Lithuania Antanas Smetona and served as the First Lady of Lithuania from April 4, 1919 to June 19, 1920 and again from December 19, 1926 to June 15, 1940. Sofija was a member of the Chodakowski noble family.