In rodents, sphenopalatine vacuities are perforations of the roof of the , the open space behind the palate, in between the . They may perforate the presphenoid or . Their development and form are variable between and within species, and features of the sphenopalatine vacuities have been used as characters in cladistic analyses. The development of sphenopalatine vacuities has also been used to distinguish among members of the Sciurini group of squirrels.
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