St. Nicholas Collegiate Reformed Protestant Dutch Church was a Reformed Protestant Dutch church in Midtown Manhattan, New York City, which was Manhattan's oldest congregation when it was demolished in 1949. The church was on the northwest corner of Fifth Avenue and 48th Street near Rockefeller Center. The church was built in 1872 to Gothic Revival designs in brownstone by architect W. Wheeler Smith and "distinguished by an elegantly tapered spire that, according to John A. Bradley in The New York Times, 'many declare…the most beautiful in this country.'" The congregation dated to 1628.