Stoke Mandeville Hospital is a large National Health Service (NHS) hospital located on the parish borders of Aylesbury and Stoke Mandeville, Buckinghamshire, England. It is managed by Buckinghamshire Healthcare NHS Trust. It was established in 1830 as a cholera hospital intentionally on the parish border between the neighbouring village of Stoke Mandeville and the town of Aylesbury to serve the residents of both settlements.