A T-cell vaccine is a vaccine designed to induce protective T-cells. T-cell vaccines are designed to induce cellular immunity. They are also referred to as cell-mediated immune (CMI) vaccines. It is thought that they can be more effective than conventional B-cell vaccines for protection from microbes that hide inside host cells, and viruses (such as HIV or influenza) that mutate rapidly. T-cell vaccines underwent clinical trials for HIV/AIDS. As of July 2012 none have been approved.
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