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Telomerase RNA component, also known as TR, TER or TERC, is an ncRNA found in eukaryotes that is a component of telomerase, the enzyme used to extend telomeres. TERC serves as a template for telomere replication (reverse transcription) by telomerase. Telomerase RNAs differ greatly in sequence and structure between vertebrates, ciliates and yeasts, but they share a 5' pseudoknot structure close to the template sequence. The vertebrate telomerase RNAs have a 3' H/ACA snoRNA-like domain.

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rdf:type
rdfs:label
  • TERC (fr)
  • テロメラーゼRNA要素 (ja)
  • Telomerase RNA component (en)
  • 端粒酶RNA組分 (zh)
rdfs:comment
  • Le TERC (pour « Telomerase RNA component ») est un ARN non codant, composant de la télomérase. Son gène est le TERC situé sur le chromosome 3 humain. (fr)
  • Telomerase RNA component, also known as TR, TER or TERC, is an ncRNA found in eukaryotes that is a component of telomerase, the enzyme used to extend telomeres. TERC serves as a template for telomere replication (reverse transcription) by telomerase. Telomerase RNAs differ greatly in sequence and structure between vertebrates, ciliates and yeasts, but they share a 5' pseudoknot structure close to the template sequence. The vertebrate telomerase RNAs have a 3' H/ACA snoRNA-like domain. (en)
  • テロメラーゼRNA要素(テロメラーゼRNAようそ、英: telomerase RNA component、略称: TERC)は真核生物に存在するノンコーディングRNAで、テロメアの伸長に用いられる酵素 テロメラーゼの構成要素である。テロメラーゼRNA構成要素、テロメラーゼRNA成分などとも呼ばれる。TERCは、テロメラーゼによるテロメアの複製(逆転写)の際の鋳型として機能する。TERCの配列と構造は脊椎動物、繊毛虫類、酵母の間で大きく異なるが、鋳型配列に近接した5'末端側にシュードノット構造が存在することは共通している。脊椎動物のTERCの3'末端にはH/ACA型snoRNA様ドメインが存在している。 (ja)
  • 端粒酶RNA組分(英語:telomerase RNA component,缩写为TERC)或称端粒酶RNA,是一種真核生物的非編碼RNA(ncRNA)。它是端粒酶的組成成分之一——端粒酶用它來延長端粒。端粒酶RNA在DNA複製過程中,爲端粒的逆轉錄過程提供模板。酵母、纖毛蟲、脊椎動物的端粒酶RNA的序列和結構都有很大不同。不過,它們的5'端靠近模板序列處,都有一個假結結構。脊椎動物端粒酶RNA的3'端有一個與snoRNA(核仁RNA)類似的結構域。 (zh)
name
  • Ciliate telomerase RNA (en)
  • Vertebrate telomerase RNA (en)
  • Saccharomyces cerevisiae telomerase RNA (en)
  • Saccharomyces telomerase (en)
foaf:depiction
  • http://commons.wikimedia.org/wiki/Special:FilePath/Illustration_-_hTR_and_associated_proteins_of_telomerase_complex.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/RF00024-rscape.svg
  • http://commons.wikimedia.org/wiki/Special:FilePath/RF00025-rscape.svg
  • http://commons.wikimedia.org/wiki/Special:FilePath/RF01050-rscape.svg
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