State Highway 49 (SH 49) is a designated north–south state highway in Texas, running from Mount Pleasant, Texas to a point on the Texas-Louisiana border about three miles (4.8 km) north of Caddo Lake, where it meets Louisiana Highway 2, which continues onward to Trees, Louisiana. SH 49 covers a total distance of 71.2 miles (114.6 km). Overall, SH 49 passes through four Texas counties: Titus, Morris, Cass, and Marion.