The Megan Mullally Show is an American talk show hosted by Megan Mullally that debuted in syndication on September 18, 2006, and was cancelled in January 2007 due to its low ratings. Early promotions for the program featured Mullally as herself and as her Will & Grace character, Karen Walker. The talk show also aired nationally on TBS and was distributed by NBCUniversal Television Distribution. The first episode featured actor Will Ferrell (who came out to the set wearing nothing but his briefs) and Jenny McCarthy.