Thomas Clark Chalmers, MD, FACP (b. December 8, 1917, New York City – d. December 27, 1995, Lebanon, New Hampshire) was famous for his role in the development of the randomized controlled trial and meta-analysis in medical research. Chalmers began his higher education as an English major at Yale College. He obtained his medical degree from Columbia University College of Physicians and Surgeons in 1943. He spent one year as an intern at the NewYork-Presbyterian Hospital, and completed his residency at the Boston City Hospital.