Tigist Assefa Tessema (born 28 March 1994) is an Ethiopian long-distance runner, a former 800 metres specialist. After her marathon debut in April 2022, she improved by over 18 minutes and set the third-fastest mark on the world all-time list (currently fifth) at the 2022 Berlin Marathon. In 2013, Assefa was the 800 metres bronze medallist at the African Junior Championships. With her 2014 personal best in the event, she became in 2022 in Berlin the first woman in history to break two minutes for 800 m and 2:20 for the marathon.