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Tomas Ganz is an American physician-scientist who has made important contributions to innate immunology and the pathophysiology of iron regulation. He was born in Prague, Czechoslovakia (now the Czech Republic) in 1948, and immigrated to the United States in 1966. He studied physics at University of California, Los Angeles (UCLA) (B.S. 1970) and obtained a Ph.D. in Applied Physics from the California Institute of Technology in 1976 and an M.D. from the University of California, Los Angeles (UCLA) in 1978. In 1983, after receiving training in pulmonology and internal medicine, he became a faculty member at UCLA in the Department of Medicine. Later he received a joint appointment in the graduate program in Cellular and Molecular Pathology. He has studied the role of small peptide mediators i

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  • Tomas Ganz (en)
  • 托马斯·甘兹 (zh)
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  • 托马斯·甘兹(Tomas Ganz),美国医学家、分子生物学家。1976年获得了加州理工学院博士学位,两年后获加州大学洛杉矶分校获医学博士学位。1983年,他在接受肺病和内科培训后成为加州大学洛杉矶分校的一名教师。后来成为的医学教授。 2001年,他和哈勃-加州大学洛杉矶分校医学中心的同事们报道了从人尿中分离防御型抗菌肽的实验。这种肽被称为铁调素,在肝脏中生产。这种肽属脊椎动物共有,后来在猪、大鼠、比目鱼中均有发现。它不但抗细菌,还能抗真菌。 (zh)
  • Tomas Ganz is an American physician-scientist who has made important contributions to innate immunology and the pathophysiology of iron regulation. He was born in Prague, Czechoslovakia (now the Czech Republic) in 1948, and immigrated to the United States in 1966. He studied physics at University of California, Los Angeles (UCLA) (B.S. 1970) and obtained a Ph.D. in Applied Physics from the California Institute of Technology in 1976 and an M.D. from the University of California, Los Angeles (UCLA) in 1978. In 1983, after receiving training in pulmonology and internal medicine, he became a faculty member at UCLA in the Department of Medicine. Later he received a joint appointment in the graduate program in Cellular and Molecular Pathology. He has studied the role of small peptide mediators i (en)
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  • Tomas Ganz is an American physician-scientist who has made important contributions to innate immunology and the pathophysiology of iron regulation. He was born in Prague, Czechoslovakia (now the Czech Republic) in 1948, and immigrated to the United States in 1966. He studied physics at University of California, Los Angeles (UCLA) (B.S. 1970) and obtained a Ph.D. in Applied Physics from the California Institute of Technology in 1976 and an M.D. from the University of California, Los Angeles (UCLA) in 1978. In 1983, after receiving training in pulmonology and internal medicine, he became a faculty member at UCLA in the Department of Medicine. Later he received a joint appointment in the graduate program in Cellular and Molecular Pathology. He has studied the role of small peptide mediators in human physiology and disease. In 2005, he received the Marcel Simon Prize of the International Bioiron Society for the discovery of the iron-regulatory hormone hepcidin and in 2014 was honored by the E. Donnall Thomas Award from the American Society of Hematology "... for his groundbreaking research in iron homeostasis, including the discovery of the iron-regulatory hormone hepcidin and investigation of its roles in iron metabolism". He is also credited with the discovery erythroferrone, the hormone produced by red cell precursors in the marrow to maintain the iron supply for the production of red cells. Currently he is a Distinguished Professor of Medicine and Pathology at the David Geffen School of Medicine at UCLA. (en)
  • 托马斯·甘兹(Tomas Ganz),美国医学家、分子生物学家。1976年获得了加州理工学院博士学位,两年后获加州大学洛杉矶分校获医学博士学位。1983年,他在接受肺病和内科培训后成为加州大学洛杉矶分校的一名教师。后来成为的医学教授。 2001年,他和哈勃-加州大学洛杉矶分校医学中心的同事们报道了从人尿中分离防御型抗菌肽的实验。这种肽被称为铁调素,在肝脏中生产。这种肽属脊椎动物共有,后来在猪、大鼠、比目鱼中均有发现。它不但抗细菌,还能抗真菌。 (zh)
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