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Trimethoxyamphetamines (TMAs) are a family of isomeric psychedelic hallucinogenic drugs. There exist six different TMAs that differ only in the position of the three methoxy groups: TMA, TMA-2, TMA-3, TMA-4, TMA-5, and TMA-6. The TMAs are analogs of the phenethylamine cactus alkaloid mescaline. The TMAs are substituted amphetamines, however, their mechanism of action is more complex than that of the unsubstituted compound amphetamine, probably involving agonist activity on serotonin receptors such as the 5HT2A receptor in addition to the generalised dopamine receptor agonism typical of most amphetamines. This action on serotonergic receptors likely underlie the psychedelic effects of these compounds. It is reported that some TMAs elicit a range of emotions ranging from sadness to empathy a

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  • 3,4,5-Trimethoxyamphetamin (de)
  • Trimetoxianfetamina (es)
  • Triméthoxyamphétamine (fr)
  • Trimethoxyamfetamine (nl)
  • Trimetoksyamfetaminy (pl)
  • Trimethoxyamphetamine (en)
  • 3,4,5-Триметоксиамфетамин (ru)
rdfs:comment
  • Las trimetoxianfetaminas, también conocidas como TMA, son una familia de drogas alucinógenas isoméricas. Existen seis isómeros de TMA distintos que difieren solo en la posición de los tres grupos metoxilo: TMA, TMA-2, TMA-3, TMA-4, TMA-5 y TMA-6. (es)
  • Les triméthoxyamphétamines (TMA) sont une famille d'isomères de substances psychotropes aux propriétés hallucinogènes. Le plus connu est le TMA-2. Elles ont été étudiées par Alexander Shulgin. Elles sont considérées comme des stupéfiants et figurent dans la Convention sur les substances psychotropes de 1971. (fr)
  • TMA – grupa psychodelicznych substancji psychoaktywnych znanych też jako trimetoksyamfetaminy. Istnieje 6 substancji w grupie TMA – TMA, TMA-2, TMA-3, TMA-4, TMA-5 i TMA-6, różnią się od siebie tylko położeniem grup metoksy przy pierścieniu benzenowym. TMA są analogami naturalnego psychodelika występującego w kaktusach Peyotl i San pedro – meskaliny. TMA bywa czasem nazywane meskalamfetaminą, jednak to TMA-2 zyskało największą sławę i popularność na rynku designer drugs. (pl)
  • 3,4,5-триметоксиамфетамин (TMA, 3,4,5-TMA, α-метилмескалин) — химическое соединение класса амфетаминов, психоделик. По структуре и фармакологическим свойствам аналогичен мескалину, от которого отличается метильной группой в позиции α. Механизм действия 3,4,5-TMA аналогичен механизму действия других классических психоделиков и основан на агонизме к 5-HT2A-рецепторам. Типичная оральная доза составляет 100—250 мг, продолжительность действия — 6-8 ч. (ru)
  • 3,4,5-Trimethoxyamphetamin (TMA) ist ein psychedelisches Halluzinogen aus der Familie der Phenethylamine. Es wurde zuerst 1948 von dem Chemiker P. Hey an der University of Leeds synthetisiert, bevor es 1960 von Alexander Shulgin wiederentdeckt und resynthetisiert wurde. TMA ist in Deutschland ein nicht verkehrsfähiges Betäubungsmittel (BtMG, Anlage I). (de)
  • Trimethoxyamphetamines (TMAs) are a family of isomeric psychedelic hallucinogenic drugs. There exist six different TMAs that differ only in the position of the three methoxy groups: TMA, TMA-2, TMA-3, TMA-4, TMA-5, and TMA-6. The TMAs are analogs of the phenethylamine cactus alkaloid mescaline. The TMAs are substituted amphetamines, however, their mechanism of action is more complex than that of the unsubstituted compound amphetamine, probably involving agonist activity on serotonin receptors such as the 5HT2A receptor in addition to the generalised dopamine receptor agonism typical of most amphetamines. This action on serotonergic receptors likely underlie the psychedelic effects of these compounds. It is reported that some TMAs elicit a range of emotions ranging from sadness to empathy a (en)
  • 3,4,5-Trimethoxyamfetamine (afgekort TMA), is een zogenaamde designer drug die structureel verwant is aan mescaline (M). Deze laatste is een fenethylamine, terwijl TMA een amfetamine (d.i. alfa-methylfenethylamine) is. Het is een psychoactive drug waarvan de eerste resultaten in de wetenschappelijke literatuur verschenen in 1955. De US Army heeft in TMA (met als codenaam EA-1319) bestudeerd als potentieel chemisch wapen. (nl)
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