The Tsay Keh Dene First Nation is one of the Sekani bands of the Northern Interior of British Columbia. Tsay Keh Dene means "People of the Mountain". While they have an office in the City of Prince George, their territories, settlements, and Indian Reserves are all to the north, in the area of Williston Lake, the creation of which flooded a large part of their territory with devastating effects on the people and their way of life.