About: Tyrosine aminotransferase

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Tyrosine aminotransferase (or tyrosine transaminase) is an enzyme present in the liver and catalyzes the conversion of tyrosine to 4-hydroxyphenylpyruvate. L-tyrosine + 2-oxoglutarate 4-hydroxyphenylpyruvate + L-glutamate In humans, the tyrosine aminotransferase protein is encoded by the TAT gene. A deficiency of the enzyme in humans can result in what is known as type II tyrosinemia, wherein there is an abundance of tyrosine as a result of tyrosine failing to undergo an aminotransferase reaction to form 4-hydroxyphenylpyruvate.

Attributes	Values
rdf:type	Thing Biomolecule Biomolecule Enzyme enzyme
rdfs:label	Tirosina aminotransferasa (es) Tyrosine aminotransferase (en)
rdfs:comment	La tirosina aminotransferasa o tirosina transaminasa (EC 2.6.1.5) es una enzima que cataliza la conversión de tirosina a 4-hidroxifenilpiruvato. L-tirosina + 2-oxoglutarato 4-hidroxifenilpiruvato + L-glutamato En humanos, la proteína tirosina aminotransferasa se encuentra codificada por el gen TAT. Una deficiencia de esta enzima en seres humanos produce la enfermedad conocida como tirosinemia tipo II, donde existe un exceso de tirosina en circulación como resultado de que la tirosina falla en convertirse en 4-hidroxifenilpiruvato. (es) Tyrosine aminotransferase (or tyrosine transaminase) is an enzyme present in the liver and catalyzes the conversion of tyrosine to 4-hydroxyphenylpyruvate. L-tyrosine + 2-oxoglutarate 4-hydroxyphenylpyruvate + L-glutamate In humans, the tyrosine aminotransferase protein is encoded by the TAT gene. A deficiency of the enzyme in humans can result in what is known as type II tyrosinemia, wherein there is an abundance of tyrosine as a result of tyrosine failing to undergo an aminotransferase reaction to form 4-hydroxyphenylpyruvate. (en)
foaf:name	Tyrosine transaminase (en)
name	Tyrosine transaminase (en)
foaf:depiction
dcterms:subject	EC 2.6.1
Wikipage page ID	11444387 (xsd:integer)
Wikipage revision ID	1118756782 (xsd:integer)
Link from a Wikipage to another Wikipage	4-hydroxyphenylpyruvic acid Pyridoxal phosphate Prosthetic group EC 2.6.1 Gene Tyrosine Tyrosinemia Tyrosinemia type II Isoleucine Aspartate transaminase C-terminus Phenylalanine Space-filling model N-terminus L-glutamate L-tyrosine 2-oxoglutarate 4-hydroxyphenylpyruvate dbr:Acyl_substitution
Link from a Wikipage to an external page	https://www.ebi.ac.uk/pdbe/pdbe-kb/proteins/P17735
sameAs	Tyrosine aminotransferase Tyrosine aminotransferase Tyrosine aminotransferase Tyrosine aminotransferase Tyrosine aminotransferase Tyrosine aminotransferase
dbp:wikiPageUsesTemplate	dbt:Amino_acid_metabolism_enzymes dbt:Clear-left dbt:Enzyme dbt:Enzymes dbt:Infobox_gene dbt:MeshName dbt:Nitrogenous_transferases dbt:Portal_bar dbt:Reflist dbt:Short_description
thumbnail	wiki-commons:Special:FilePath/3DYD.png?width=300
caption	Human tyrosine aminotransferase complexed with pyridoxal phosphate . (en)
CAS number	9014 (xsd:integer)
EC number	2.600000 (xsd:double)
GO code	80130 (xsd:integer)
IUBMB EC number	2 (xsd:integer)
has abstract	La tirosina aminotransferasa o tirosina transaminasa (EC 2.6.1.5) es una enzima que cataliza la conversión de tirosina a 4-hidroxifenilpiruvato. L-tirosina + 2-oxoglutarato 4-hidroxifenilpiruvato + L-glutamato En humanos, la proteína tirosina aminotransferasa se encuentra codificada por el gen TAT. Una deficiencia de esta enzima en seres humanos produce la enfermedad conocida como tirosinemia tipo II, donde existe un exceso de tirosina en circulación como resultado de que la tirosina falla en convertirse en 4-hidroxifenilpiruvato. (es) Tyrosine aminotransferase (or tyrosine transaminase) is an enzyme present in the liver and catalyzes the conversion of tyrosine to 4-hydroxyphenylpyruvate. L-tyrosine + 2-oxoglutarate 4-hydroxyphenylpyruvate + L-glutamate In humans, the tyrosine aminotransferase protein is encoded by the TAT gene. A deficiency of the enzyme in humans can result in what is known as type II tyrosinemia, wherein there is an abundance of tyrosine as a result of tyrosine failing to undergo an aminotransferase reaction to form 4-hydroxyphenylpyruvate. (en)
prov:wasDerivedFrom	wikipedia-en:Tyrosine_aminotransferase?oldid=1118756782&ns=0
page length (characters) of wiki page	8385 (xsd:nonNegativeInteger)
EC number	2.6.1.5
foaf:isPrimaryTopicOf	wikipedia-en:Tyrosine_aminotransferase
is Link from a Wikipage to another Wikipage of	dbr:Fumarylacetoacetate_hydrolase Tat Tyrosinemia Tyrosinemia type II Nitinol biocompatibility 3-O-Methyldopa dbr:4-Hydroxyphenylpyruvic_acid Glucocorticoid Cathepsin T L-tyrosine:2-oxoglutarate aminotransferase EC 2.6.1.5 TAT (gene) Tyrosine transaminase
is Wikipage redirect of	L-tyrosine:2-oxoglutarate aminotransferase EC 2.6.1.5 TAT (gene) Tyrosine transaminase
is foaf:primaryTopic of	wikipedia-en:Tyrosine_aminotransferase

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