USS Denebola (AD-12) was an Altair-class destroyer tender named for Denebola, the second-brightest star in the constellation Leo. Originally built in 1919 as SS Edgewood by Skinner and Eddy of Seattle, Washington, then transferred from the Shipping Board on 4 November 1921 and converted for naval use at Philadelphia Navy Yard. She was commissioned as USS Denebola (AD-12) on 28 November 1921.