USS YP-346 was a yard patrol boat in the U.S. Navy during World War II. The vessel began its career as the fishing vessel Prospect in 1938. Seized by the U.S. Navy in 1941 after the Attack on Pearl Harbor, it ferried supplies throughout the Pacific theater and was involved in the Guadalcanal campaign. The ship was destroyed by the Japanese light cruiser Sendai after its convoy was intercepted while returning to Tulagi harbor.