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In enzymology, an unspecific monooxygenase (EC 1.14.14.1) is an enzyme that catalyzes the chemical reaction RH + reduced flavoprotein + O2 ROH + oxidized flavoprotein + H2O The 3 substrates of this enzyme are RH (reduced substrate), , and O2, whereas its 3 products are ROH (oxidized substrate), , and H2O.

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  • Monoossigenasi aspecifica (it)
  • 非特異的モノオキシゲナーゼ (ja)
  • Unspecific monooxygenase (en)
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  • 非特異的モノオキシゲナーゼ（unspecific monooxygenase）は、次の化学反応を触媒する酸化還元酵素である。 R-H + 還元型フラボタンパク質 + O2 ROH + 酸化型フラボタンパク質 + H2O この酵素の基質はR-H、還元型フラボタンパク質とO2で、生成物はR-OH、酸化型フラボタンパク質、H2Oである。補因子としてヘムを用いる。 組織名はsubstrate,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)で、別名にmicrosomal monooxygenase、xenobiotic monooxygenase、aryl-4-monooxygenase、aryl hydrocarbon hydroxylase、microsomal P-450、flavoprotein-linked monooxygenase、flavoprotein monooxygenaseがある。 (ja)
  • La monoossigenasi aspecifica è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: RH + flavoproteina ridotta + O2 ⇄ ROH + flavoproteina ossidata + H2O Si tratta di un gruppo di proteine eme-tiolate (P-450) che agiscono su un ampio spettro di substrati, tra cui molti xenobiotici, steroidi, acidi grassi, vitamine e prostaglandine. Le reazioni catalizzate includono idrossilazione, epossidazione, N-ossidazione, , deamminazione, N-, S- e O-dealchilazioni. (it)
  • In enzymology, an unspecific monooxygenase (EC 1.14.14.1) is an enzyme that catalyzes the chemical reaction RH + reduced flavoprotein + O2 ROH + oxidized flavoprotein + H2O The 3 substrates of this enzyme are RH (reduced substrate), , and O2, whereas its 3 products are ROH (oxidized substrate), , and H2O. (en)
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  • unspecific monooxygenase (en)
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  • unspecific monooxygenase (en)
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  • In enzymology, an unspecific monooxygenase (EC 1.14.14.1) is an enzyme that catalyzes the chemical reaction RH + reduced flavoprotein + O2 ROH + oxidized flavoprotein + H2O The 3 substrates of this enzyme are RH (reduced substrate), , and O2, whereas its 3 products are ROH (oxidized substrate), , and H2O. This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor. The systematic name of this enzyme class is substrate,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing). Other names in common use include microsomal monooxygenase, xenobiotic monooxygenase, aryl-4-monooxygenase, aryl hydrocarbon hydroxylase, microsomal P-450, flavoprotein-linked monooxygenase, and flavoprotein monooxygenase. This enzyme participates in 7 metabolic pathways: fatty acid metabolism, , gamma-hexachlorocyclohexane degradation, tryptophan metabolism, arachidonic acid metabolism, linoleic acid metabolism, and . It employs one cofactor, heme. (en)
  • 非特異的モノオキシゲナーゼ（unspecific monooxygenase）は、次の化学反応を触媒する酸化還元酵素である。 R-H + 還元型フラボタンパク質 + O2 ROH + 酸化型フラボタンパク質 + H2O この酵素の基質はR-H、還元型フラボタンパク質とO2で、生成物はR-OH、酸化型フラボタンパク質、H2Oである。補因子としてヘムを用いる。 組織名はsubstrate,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)で、別名にmicrosomal monooxygenase、xenobiotic monooxygenase、aryl-4-monooxygenase、aryl hydrocarbon hydroxylase、microsomal P-450、flavoprotein-linked monooxygenase、flavoprotein monooxygenaseがある。 (ja)
  • La monoossigenasi aspecifica è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: RH + flavoproteina ridotta + O2 ⇄ ROH + flavoproteina ossidata + H2O Si tratta di un gruppo di proteine eme-tiolate (P-450) che agiscono su un ampio spettro di substrati, tra cui molti xenobiotici, steroidi, acidi grassi, vitamine e prostaglandine. Le reazioni catalizzate includono idrossilazione, epossidazione, N-ossidazione, , deamminazione, N-, S- e O-dealchilazioni. Insieme alla NADPH-emoproteina reduttasi (numero EC 1.6.2.4), essa forma un sistema in cui due equivalenti di riduzione sono forniti da NADPH. Alcune delle reazioni attribuite alla alcano 1-monoossigenasi (numero EC 1.14.15.3 sono in realtà catalizzate dalla monoossigenasi aspecifica. (it)
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  • 1.14.14.1
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