About: Verruculogen

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Verruculogen is a mycotoxin produced by certain strains of aspergillus that belongs to a class of naturally occurring 2,5-diketopiperazines. It is an annulated analogue of cyclo(L-Trp-L-Pro) which belongs to the most abundant and structurally diverse class of tryptophan-proline 2,5-diketopiperazine natural products. It produces tremors in mice due to its neurotoxic properties. It also tested positive in a Salmonella/mammalian microsome assay and was shown to be genotoxic. It is a potent blocker of calcium-activated potassium channels.

Attributes	Values
rdf:type	Thing dul:ChemicalObject chemical substance Chemical compound yago:WikicatMolecularFormulas yago:WikicatMycotoxins yago:WikicatOrganicPeroxides yago:Abstraction100002137 yago:Agent114778436 yago:CausalAgent100007347 yago:ChemicalAgent114779550 yago:Communication100033020 yago:Formula106816935 yago:HydrogenPeroxide114781225 yago:Matter100020827 yago:Message106598915 yago:MolecularFormula106817173 yago:Mycotoxin115036536 yago:Oxidant114780040 yago:PhysicalEntity100001930 yago:PlantToxin115036638 yago:Poison115032376 chemical compound yago:Statement106722453 yago:Substance100020090 yago:Toxin115034074
rdfs:label	Verruculogen (ca) Verruculogen (en)
rdfs:comment	El verruculogen és una micotoxina que prové de les espècies Aspergillus fumigatus i . La seva perillositat rau en el fet que és el causant d'una síndrome neurotòxica particular que afecta el bestiar, conegut com a "staggers sindrome". El verruculogen pertany al grup de metabòlits secundaris tòxics, coneguts com a . Té la següent fórmula química C27H33N₃O₇) És una molècula qualificada com a tòxica. (ca) Verruculogen is a mycotoxin produced by certain strains of aspergillus that belongs to a class of naturally occurring 2,5-diketopiperazines. It is an annulated analogue of cyclo(L-Trp-L-Pro) which belongs to the most abundant and structurally diverse class of tryptophan-proline 2,5-diketopiperazine natural products. It produces tremors in mice due to its neurotoxic properties. It also tested positive in a Salmonella/mammalian microsome assay and was shown to be genotoxic. It is a potent blocker of calcium-activated potassium channels. (en)
foaf:depiction
dcterms:subject	Indole alkaloids Organic peroxides Diketopiperazines Mycotoxins
Wikipage page ID	40254502 (xsd:integer)
Wikipage revision ID	1084291830 (xsd:integer)
Link from a Wikipage to another Wikipage	Indole alkaloids Organic peroxides Calcium-activated potassium channel Fumitremorgin 2,5-diketopiperazine Diketopiperazines Mycotoxins Aspergillus Borylation Mycotoxin Annulated Genotoxic
sameAs	Verruculogen Verruculogen Verruculogen Verruculogen Verruculogen Verruculogen Verruculogen
dbp:wikiPageUsesTemplate	dbt:Chembox dbt:Chembox_Hazards dbt:Chembox_Identifiers dbt:Chembox_Properties dbt:Reflist
thumbnail	wiki-commons:Special:FilePath/Verruculogen.svg?width=300
ImageFile	Verruculogen.svg (en)
imagesize	200 (xsd:integer)
PIN	-1010 (xsd:integer)
has abstract	El verruculogen és una micotoxina que prové de les espècies Aspergillus fumigatus i . La seva perillositat rau en el fet que és el causant d'una síndrome neurotòxica particular que afecta el bestiar, conegut com a "staggers sindrome". El verruculogen pertany al grup de metabòlits secundaris tòxics, coneguts com a . Té la següent fórmula química C27H33N₃O₇) És una molècula qualificada com a tòxica. (ca) Verruculogen is a mycotoxin produced by certain strains of aspergillus that belongs to a class of naturally occurring 2,5-diketopiperazines. It is an annulated analogue of cyclo(L-Trp-L-Pro) which belongs to the most abundant and structurally diverse class of tryptophan-proline 2,5-diketopiperazine natural products. It produces tremors in mice due to its neurotoxic properties. It also tested positive in a Salmonella/mammalian microsome assay and was shown to be genotoxic. It is a potent blocker of calcium-activated potassium channels. (en)
gold:hypernym	Mycotoxin
prov:wasDerivedFrom	wikipedia-en:Verruculogen?oldid=1084291830&ns=0
page length (characters) of wiki page	2557 (xsd:nonNegativeInteger)
IUPAC name	(5R,10S,10aR,14aS,15bS)-10,10a-Dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methylprop-1-en-1-yl)-1,10,10a,12,13,14,14a,15b-octahydro-5H,15H-3,4-dioxa-5a,11a,15a-triazacycloocta[lm]indeno[5,6-b]fluorene-11,15(2H)-dione (en)
foaf:isPrimaryTopicOf	wikipedia-en:Verruculogen
is Link from a Wikipage to another Wikipage of	List of biomolecules Penicillium raistrickii Penicillium verruculosum 2,5-Diketopiperazine C27H33N3O7 Penicillium estinogenum Foodborne illness
is Wikipage redirect of	C27H33N3O7
is foaf:primaryTopic of	wikipedia-en:Verruculogen

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