Virodene was claimed to be an HIV/AIDS drug developed in South Africa, but was rejected by the scientific community. Controversy surrounded the research procedures, political interference and the safety and efficacy of the drug itself, the main active ingredient of which is the highly toxic industrial solvent dimethylformamide. Calls were made for an investigation of South African President Thabo Mbeki's involvement in support or funding of the company.
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| - Virodene es un controvertido fármaco desarrollado en Sudáfrica contra el SIDA, pero fue rechazado por la comunidad científica. La controversia rodea a los procedimientos de investigación, la interferencia política y la seguridad y la eficacia de la droga en sí, el principal ingrediente activo es el solvente industrial dimetilformamida. Se han hecho llamados en algunos círculos para que se investigue al presidente sudafricano la participación de Thabo Mbeki en apoyo a la financiación de la empresa. (es)
- Virodene was claimed to be an HIV/AIDS drug developed in South Africa, but was rejected by the scientific community. Controversy surrounded the research procedures, political interference and the safety and efficacy of the drug itself, the main active ingredient of which is the highly toxic industrial solvent dimethylformamide. Calls were made for an investigation of South African President Thabo Mbeki's involvement in support or funding of the company. (en)
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| - Virodene es un controvertido fármaco desarrollado en Sudáfrica contra el SIDA, pero fue rechazado por la comunidad científica. La controversia rodea a los procedimientos de investigación, la interferencia política y la seguridad y la eficacia de la droga en sí, el principal ingrediente activo es el solvente industrial dimetilformamida. Michelle Olga Patricia Visser , trabajando como técnico médico en el hospital de Pretoria, dice que descubrió las propiedades antibacterianas de la DMF mientras se realizan experimentos para congelar corazón de los animales que utilizan esta sustancia. Junto con su marido, hombre de negocios, Jacques Siegfried "Zigi" Visser, se administró el fármaco a 11 pacientes sin aprobación. Se les reprendió por esas acciones y el Consejo sudafricano de Control de Medicamentos ha bloqueado más ensayos humanos. Más ensayos humanos se llevaron a cabo en Tanzania en 2000, incluso después de que el Consejo sudafricano de Control de Medicamentos dictaminó que tales ensayos no eran ético y en contravención de la ley y se negó el permiso para ensayos en humanos en 1998. La agencia de salud de Tanzania, NIMR, también rechazó las propuestas de ensayos con seres humanos, pero los Vissers se acercó a la Fuerza de Defensa de Tanzania directamente y llevó a cabo las pruebas en los hospitales militares. Se han hecho llamados en algunos círculos para que se investigue al presidente sudafricano la participación de Thabo Mbeki en apoyo a la financiación de la empresa. (es)
- Virodene was claimed to be an HIV/AIDS drug developed in South Africa, but was rejected by the scientific community. Controversy surrounded the research procedures, political interference and the safety and efficacy of the drug itself, the main active ingredient of which is the highly toxic industrial solvent dimethylformamide. , working as a medical technician at Pretoria Hospital (now Steve Biko Academic Hospital), said that she discovered the anti-bacterial properties of dimethylformamide while conducting experiments to freeze animal hearts using this substance. In conjunction with her businessman husband, Jacques Siegfried "Zigi" Visser, she administered the drug to 11 patients without approval. They were rebuked for these actions and the blocked further human trials. Two cardio-thoraic surgeons at the University of Pretoria, Professor Dirk du Plessis and Dr Kallie Landauer, were also rebuked. More human trials were conducted in Tanzania in 2000 even after the South African Medicines Control Council ruled that such trials would be unethical and in contravention of the law and refused permission for human trials in 1998. The Tanzania health agency, NIMR, also rejected proposals for human trials, but the Vissers approached the Tanzanian Defence Force directly and conducted the trials in military hospitals. Calls were made for an investigation of South African President Thabo Mbeki's involvement in support or funding of the company. (en)
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