About: WW domain

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The WW domain, (also known as the rsp5-domain or WWP repeating motif) is a modular protein domain that mediates specific interactions with protein ligands. This domain is found in a number of unrelated signaling and structural proteins and may be repeated up to four times in some proteins. Apart from binding preferentially to proteins that are proline-rich, with particular proline-motifs, [AP]-P-P-[AP]-Y, some WW domains bind to phosphoserine- phosphothreonine-containing motifs.

Attributes	Values
rdf:type	Thing Biomolecule Biomolecule Protein yago:Abstraction100002137 yago:Family108078020 yago:Group100031264 yago:Organization108008335 yago:YagoLegalActor yago:YagoLegalActorGeo yago:YagoPermanentlyLocatedEntity protein yago:SocialGroup107950920 yago:Unit108189659
rdfs:label	WW-Domäne (de) WWドメイン (ja) WW domain (en) WW结构域 (zh)
rdfs:comment	Bei der WW, WWP-Domäne oder auch Rsp5-Domäne handelt es sich um eine Proteindomäne verschiedener Proteine. Sie tritt mit verschiedenen Protein-Liganden in Wechselwirkung. Sie kann weiterhin an Prolin-reiche Domänen/Proteine binden, an [AP]-P-P-[AP]-Y und an Domänen, die - beinhalten. (de) The WW domain, (also known as the rsp5-domain or WWP repeating motif) is a modular protein domain that mediates specific interactions with protein ligands. This domain is found in a number of unrelated signaling and structural proteins and may be repeated up to four times in some proteins. Apart from binding preferentially to proteins that are proline-rich, with particular proline-motifs, [AP]-P-P-[AP]-Y, some WW domains bind to phosphoserine- phosphothreonine-containing motifs. (en) WWドメイン（英: WW domain、rsp5ドメイン、WWPリピートモチーフとしても知られる）は、タンパク質のリガンドとの特異的相互作用を媒介する、モジュール状のタンパク質ドメインである。WWドメインは、無関係な多くのシグナル伝達タンパク質や構造タンパク質に見つかり、一部のタンパク質では最大4つのリピート構造が存在する。プロリンに富む、特に[AP]-P-P-[AP]-Yからなるモチーフをタンパク質に結合することに加え、WWドメインの一部はホスホセリンやホスホスレオニンを含むモチーフに結合する。 (ja) WW結構域又被稱為雙色胺酸功能區、Rsp5 或 WWP domain。是由30-40個胺基酸所組成的結構緊密的三股反平行。因結構域上有2個高度保守的色胺酸，縮寫為“W”，因此被稱為WW結構域。 (zh)
name	WW domain (en)
foaf:depiction
dcterms:subject	Protein domains
Wikipage page ID	26055024 (xsd:integer)
Wikipage revision ID	1050185588 (xsd:integer)
Link from a Wikipage to another Wikipage	Proline Protein-protein interaction Endohedral fullerene Mouse Structural motif David E. Shaw Algorithm Hypertension Beta sheet dbr:Dystrophin Saccharomyces cerevisiae Proteome Genome Endohedral metallofullerenol Protein module Antineoplastic Magnetic resonance imaging Tryptophan PIN1 Hippo signaling pathway Protein domain Molecular dynamics Protein folding Protein domains APBB1 Phosphoserine Rat Nuclear magnetic resonance spectroscopy of proteins SMAD (protein) Nicotiana tabacum Exon Utrophin NEDD4 Oncogene Phosphorylation Statistical potential Rama Ranganathan YAP1 Serine-threonine kinase Phosphothreonine Liddle syndrome Co-activator
sameAs	WW domain WW domain WW domain WW domain WW domain WW domain WW domain
dbp:wikiPageUsesTemplate	dbt:ELM dbt:Infobox_protein_family dbt:InterPro_content dbt:Reflist
thumbnail	wiki-commons:Special:FilePath/PDB_1pin_EBI.jpg?width=300
PROSITE	PDOC50020 (en)
SCOP	1 (xsd:integer)
caption	Structure of the human mitotic rotamase Pin1. (en)
InterPro	IPR001202 (en)
Pfam	PF00397 (en)
symbol	WW (en)
has abstract	Bei der WW, WWP-Domäne oder auch Rsp5-Domäne handelt es sich um eine Proteindomäne verschiedener Proteine. Sie tritt mit verschiedenen Protein-Liganden in Wechselwirkung. Sie kann weiterhin an Prolin-reiche Domänen/Proteine binden, an [AP]-P-P-[AP]-Y und an Domänen, die - beinhalten. (de) The WW domain, (also known as the rsp5-domain or WWP repeating motif) is a modular protein domain that mediates specific interactions with protein ligands. This domain is found in a number of unrelated signaling and structural proteins and may be repeated up to four times in some proteins. Apart from binding preferentially to proteins that are proline-rich, with particular proline-motifs, [AP]-P-P-[AP]-Y, some WW domains bind to phosphoserine- phosphothreonine-containing motifs. (en) WWドメイン（英: WW domain、rsp5ドメイン、WWPリピートモチーフとしても知られる）は、タンパク質のリガンドとの特異的相互作用を媒介する、モジュール状のタンパク質ドメインである。WWドメインは、無関係な多くのシグナル伝達タンパク質や構造タンパク質に見つかり、一部のタンパク質では最大4つのリピート構造が存在する。プロリンに富む、特に[AP]-P-P-[AP]-Yからなるモチーフをタンパク質に結合することに加え、WWドメインの一部はホスホセリンやホスホスレオニンを含むモチーフに結合する。 (ja) WW結構域又被稱為雙色胺酸功能區、Rsp5 或 WWP domain。是由30-40個胺基酸所組成的結構緊密的三股反平行。因結構域上有2個高度保守的色胺酸，縮寫為“W”，因此被稱為WW結構域。 (zh)
CDD	cd00201 (en)
gold:hypernym	Domain
prov:wasDerivedFrom	wikipedia-en:WW_domain?oldid=1050185588&ns=0
page length (characters) of wiki page	22811 (xsd:nonNegativeInteger)
Symbol	WW
foaf:isPrimaryTopicOf	wikipedia-en:WW_domain
is Link from a Wikipage to another Wikipage of	Endohedral fullerene Membrane-associated guanylate kinase Beta hairpin

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