Westdene is a suburb of Johannesburg, South Africa. Westdene lies between the historic suburb of Sophiatown and Melville with the Melville Koppies West nature reserve to the north of the suburb. Westdene derives its name from its location, literally meaning west-valley. 'West' since it is located west from the city centre and with 'dene' derived from the Old English denu, meaning valley.