Whychus Creek is a tributary of the Deschutes River in Deschutes and Jefferson counties in the U.S. state of Oregon. Formerly named Squaw Creek, considered derogatory in the 21st century, it was renamed in 2006. Explorer John C. Frémont camped along the stream in 1843 but did not identify it by name. Robert S. Williamson, a surveyor who camped there in 1855, said its Indian (Native American) name was Why-chus.