William Bull (1683 – March 21, 1755) was a landowner and politician in the Province of South Carolina. He was a captain in the Tuscarora War and then a colonel in the Yamasee War before he became the Commissioner of Indian Affairs in 1721. He served on the governor's council and was the lieutenant governor under James Glen from 1738 to 1755 and acting governor from 1738 to 1744. In 1733, he assisted James Oglethorpe in the founding of the new Province of Georgia, laying out the town of Savannah, whose Bull Street is named for him. His father, Stephen Bull, was Lord Ashley's deputy and one of the leaders of the expedition that came from England in 1670 and settled Charles Town.