Wooleen Station is a pastoral lease that was previously operated as a sheep station and currently runs cattle. The station was established in 1886 in the Murchison region of Western Australia that is bisected by the Murchison River. The station is situated approximately 680 kilometres (423 mi) north of Perth in the Shire of Murchison. The property lies just west of Boolardy Station, now the home of the Murchison Radio-astronomy Observatory, which incorporates the Square Kilometre Array (SKA).