Wrestle Grand Slam in Tokyo Dome was a professional wrestling pay-per-view (PPV) event produced by New Japan Pro-Wrestling (NJPW). The event took place on July 25, 2021, at the Tokyo Dome in Tokyo, Japan. The event was originally scheduled to take place on May 29 but was postponed to July 25 due to the state of emergency in Japan because of the COVID-19 pandemic.