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YOYO-1 is a green fluorescent dye used in DNA staining. It belongs to the family of monomethine cyanine dyes and is a tetracationic homodimer of (abbreviated YO, hence the name YOYO), typically available as tetraiodide salt. In aqueous buffer, free YOYO-1 dye (absorption: λmax 458 nm, emission: λmax 564 nm) has very low fluorescence quantum yield, however the intensity of fluorescence increases 3200 times upon binding through bis-intercalation to double-stranded DNA (absorption: λmax 489 nm, emission: λmax 509 nm).

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rdfs:label
  • YOYO-1 (en)
rdfs:comment
  • YOYO-1 is a green fluorescent dye used in DNA staining. It belongs to the family of monomethine cyanine dyes and is a tetracationic homodimer of (abbreviated YO, hence the name YOYO), typically available as tetraiodide salt. In aqueous buffer, free YOYO-1 dye (absorption: λmax 458 nm, emission: λmax 564 nm) has very low fluorescence quantum yield, however the intensity of fluorescence increases 3200 times upon binding through bis-intercalation to double-stranded DNA (absorption: λmax 489 nm, emission: λmax 509 nm). (en)
foaf:depiction
  • http://commons.wikimedia.org/wiki/Special:FilePath/YOYO-1_fluorescent_dye.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/YOYO-1_fluorescent_dye_synthesis.png
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  • YOYO-1_fluorescent_dye.png (en)
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OtherNames
  • YOYO, YOYO-1, YoYo-1 (en)
PIN
  • [12Z,16Z]-13,7,7,11,11,173-Hexamethyl-13H,173H-7,11-diaza-31λ5,151λ5-3,15-diquinolina-1,17-bisheptadecaphane-12,16-diene-7,11-diium-31,151-bis tetraiodide (en)
has abstract
  • YOYO-1 is a green fluorescent dye used in DNA staining. It belongs to the family of monomethine cyanine dyes and is a tetracationic homodimer of (abbreviated YO, hence the name YOYO), typically available as tetraiodide salt. In aqueous buffer, free YOYO-1 dye (absorption: λmax 458 nm, emission: λmax 564 nm) has very low fluorescence quantum yield, however the intensity of fluorescence increases 3200 times upon binding through bis-intercalation to double-stranded DNA (absorption: λmax 489 nm, emission: λmax 509 nm). (en)
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alternative name
  • YOYO, YOYO-1, YoYo-1 (en)
IUPAC name
  • [12(2)Z,16(172)Z]-13,7,7,11,11,173-Hexamethyl-13H,173H-7,11-diaza-31λ5,151λ5-3(4,1),15(1,4)-diquinolina-1,17(2)-bis([1,3]benzoxazola)heptadecaphane-12(2),16(172)-diene-7,11-diium-31,151-bis(ylium) tetraiodide (en)
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