The Yodo Line (予土線, Yodo-sen) is a railway line in Shikoku, Japan, operated by Shikoku Railway Company (JR Shikoku). It connects Kubokawa Station, Shimanto, Takaoka District in Kōchi Prefecture and Uwajima in Ehime Prefecture. Its name comes from the ancient provinces of Iyo (伊予) (now Ehime Prefecture) and Tosa (土佐) (now Kōchi Prefecture), which the line connects.