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Zenker's degeneration is a severe glassy or waxy hyaline degeneration or necrosis of skeletal muscles in acute infectious diseases; a prototype of coagulative necrosis. The condition was named by Friedrich Albert von Zenker. It is a hyaline degeneration of skeletal muscles such as rectus abdominis and diaphragm, and occurs in severe toxaemia as typhoid fever. It is also seen in electrical burns. Grossly the muscles appear pale and friable; microscopically, the muscle fibres are swollen, have a loss of cross striations, and show a hyaline appearance. Rupture and small hemorrhage may complicate the lesion. Coagulative necrosis occurs here.

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  • تنكس زينكر (ar)
  • Degenerazione di Zenker (it)
  • Zenker's degeneration (en)
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  • تنكس زينكر (بالإنجليزية: Zenker's Degeneration)‏ هو زجاجي أو شمعي، أو نخر في العضلات الهيكيلية يحدث في حالات الأمراض المعدية الحادة. تسمى هذه الحالة نسبة إلى فريدريش ألبرت فون زنكر. يحدث تنكس زينكر في العضلات الهيكلية مثل الحجاب الحاجز والعضلة المستقيمة البطنية بسبب حالات تسمم الدم الحادة مثل حمى التيفوئيد. تظهر العضلة شاحبة وقابلة للتفتت. ومجهريا، تظهر الألياف العضلية متورمة، وفاقدة للتخطيط العرضي، وتُظهر مظهرا زجاجيا. (ar)
  • Zenker's degeneration is a severe glassy or waxy hyaline degeneration or necrosis of skeletal muscles in acute infectious diseases; a prototype of coagulative necrosis. The condition was named by Friedrich Albert von Zenker. It is a hyaline degeneration of skeletal muscles such as rectus abdominis and diaphragm, and occurs in severe toxaemia as typhoid fever. It is also seen in electrical burns. Grossly the muscles appear pale and friable; microscopically, the muscle fibres are swollen, have a loss of cross striations, and show a hyaline appearance. Rupture and small hemorrhage may complicate the lesion. Coagulative necrosis occurs here. (en)
  • La degenerazione di Zenker è una grave degenerazione ialina o necrosi dei muscoli scheletrici che avviene nelle malattie infettive acute. La condizione prende il nome da Friedrich Albert von Zenker. Si tratta di una degenerazione ialina dei muscoli scheletrici come retto addominale e del diaframma e si verifica nei casi di tossiemia grave come la febbre tifoide. Grossolanamente i muscoli appaiono pallidi e friabili; al microscopio, le fibre muscolari sono gonfie, hanno una perdita di striature trasversali e mostrano un aspetto ialino. Piccole emorragie possono complicare la lesione. (it)
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  • تنكس زينكر (بالإنجليزية: Zenker's Degeneration)‏ هو زجاجي أو شمعي، أو نخر في العضلات الهيكيلية يحدث في حالات الأمراض المعدية الحادة. تسمى هذه الحالة نسبة إلى فريدريش ألبرت فون زنكر. يحدث تنكس زينكر في العضلات الهيكلية مثل الحجاب الحاجز والعضلة المستقيمة البطنية بسبب حالات تسمم الدم الحادة مثل حمى التيفوئيد. تظهر العضلة شاحبة وقابلة للتفتت. ومجهريا، تظهر الألياف العضلية متورمة، وفاقدة للتخطيط العرضي، وتُظهر مظهرا زجاجيا. (ar)
  • Zenker's degeneration is a severe glassy or waxy hyaline degeneration or necrosis of skeletal muscles in acute infectious diseases; a prototype of coagulative necrosis. The condition was named by Friedrich Albert von Zenker. It is a hyaline degeneration of skeletal muscles such as rectus abdominis and diaphragm, and occurs in severe toxaemia as typhoid fever. It is also seen in electrical burns. Grossly the muscles appear pale and friable; microscopically, the muscle fibres are swollen, have a loss of cross striations, and show a hyaline appearance. Rupture and small hemorrhage may complicate the lesion. Coagulative necrosis occurs here. (en)
  • La degenerazione di Zenker è una grave degenerazione ialina o necrosi dei muscoli scheletrici che avviene nelle malattie infettive acute. La condizione prende il nome da Friedrich Albert von Zenker. Si tratta di una degenerazione ialina dei muscoli scheletrici come retto addominale e del diaframma e si verifica nei casi di tossiemia grave come la febbre tifoide. Grossolanamente i muscoli appaiono pallidi e friabili; al microscopio, le fibre muscolari sono gonfie, hanno una perdita di striature trasversali e mostrano un aspetto ialino. Piccole emorragie possono complicare la lesione. (it)
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