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In enzymology, a (R)-2-hydroxyacid dehydrogenase (EC 1.1.1.272) is an enzyme that catalyzes the chemical reaction (2R)-3-sulfolactate + NAD(P)+ 3-sulfopyruvate + NAD(P)H + H+ The 3 substrates of this enzyme are , NAD+, and NADP+, whereas its 4 products are , NADH, NADPH, and H+. This enzyme is important in the metabolism of archaea, particularly their biosynthesis of coenzymes such as coenzyme M, tetrahydromethanopterin and methanofuran.

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  • (R)-2-hydroxyacid dehydrogenase (en)
  • (R)-2-idrossiacido deidrogenasi (it)
  • (R)-2-ヒドロキシ酸デヒドロゲナーゼ (ja)
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  • (R)-2-ヒドロキシ酸デヒドロゲナーゼ((R)-2-hydroxyacid dehydrogenase, ComC)は、次の化学反応を触媒する酸化還元酵素である。 (2R)-3-スルホ乳酸 + NAD(P)+ 3-スルホピルビン酸 + NAD(P)H + H+ すなわち、この酵素の基質はとNAD(P)+、生成物はとNAD(P)HとH+である。 組織名は(R)-2-hydroxyacid:NAD(P)+ oxidoreductaseで、別名に(R)-sulfolactate:NAD(P)+ oxidoreductase, L-sulfolactate dehydrogenase, (R)-sulfolactate dehydrogenaseがある。 (ja)
  • La (R)-2-idrossiacido deidrogenasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: (2R)-3- + NAD(P)+ ⇄ 3- + NAD(P)H + H+ Questa deidrogenasi agisce anche sul (S)-malato e sul (S)-2-, cioè su substrati con la stessa configurazione del (R)-sulfolattato. (it)
  • In enzymology, a (R)-2-hydroxyacid dehydrogenase (EC 1.1.1.272) is an enzyme that catalyzes the chemical reaction (2R)-3-sulfolactate + NAD(P)+ 3-sulfopyruvate + NAD(P)H + H+ The 3 substrates of this enzyme are , NAD+, and NADP+, whereas its 4 products are , NADH, NADPH, and H+. This enzyme is important in the metabolism of archaea, particularly their biosynthesis of coenzymes such as coenzyme M, tetrahydromethanopterin and methanofuran. (en)
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  • (R)-2-hydroxyacid dehydrogenase (en)
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  • In enzymology, a (R)-2-hydroxyacid dehydrogenase (EC 1.1.1.272) is an enzyme that catalyzes the chemical reaction (2R)-3-sulfolactate + NAD(P)+ 3-sulfopyruvate + NAD(P)H + H+ The 3 substrates of this enzyme are , NAD+, and NADP+, whereas its 4 products are , NADH, NADPH, and H+. This enzyme is important in the metabolism of archaea, particularly their biosynthesis of coenzymes such as coenzyme M, tetrahydromethanopterin and methanofuran. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-2-hydroxyacid:NAD(P)+ oxidoreductase. Other names in common use include (R)-sulfolactate:NAD(P)+ oxidoreductase, L-sulfolactate dehydrogenase, ComC, and (R)-sulfolactate dehydrogenase. (en)
  • (R)-2-ヒドロキシ酸デヒドロゲナーゼ((R)-2-hydroxyacid dehydrogenase, ComC)は、次の化学反応を触媒する酸化還元酵素である。 (2R)-3-スルホ乳酸 + NAD(P)+ 3-スルホピルビン酸 + NAD(P)H + H+ すなわち、この酵素の基質はとNAD(P)+、生成物はとNAD(P)HとH+である。 組織名は(R)-2-hydroxyacid:NAD(P)+ oxidoreductaseで、別名に(R)-sulfolactate:NAD(P)+ oxidoreductase, L-sulfolactate dehydrogenase, (R)-sulfolactate dehydrogenaseがある。 (ja)
  • La (R)-2-idrossiacido deidrogenasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: (2R)-3- + NAD(P)+ ⇄ 3- + NAD(P)H + H+ Questa deidrogenasi agisce anche sul (S)-malato e sul (S)-2-, cioè su substrati con la stessa configurazione del (R)-sulfolattato. (it)
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  • 1.1.1.272
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