The 1890–91 season was Burslem Port Vale's first season in the newly-formed Midland League. They finished in eighth-place, having only picked up two points away from home. They failed to go on any cup runs and were in fact beaten by a club record 12–0 margin by Aston Villa in the Second Round of the Staffordshire Senior Cup. They did though share the North Staffordshire Challenge Cup after holding Stoke to a draw in the final.