The 1944 United States Senate election in Ohio took place on November 7, 1944. Incumbent Republican Senator Robert A. Taft, first elected in the Republican wave of 1938, was narrowly elected to a second term in office over Democratic former Lieutenant Governor William G. Pickrel, winning 71 of Ohio's 88 counties. Despite Pickrel winning the state's largest urban centers such as Cleveland, his margins there were overcome by Taft's strong showings in the rural areas and small towns. Nevertheless, at less than a point, Taft's victory was significantly smaller then his 7 point win in 1938.