The 1949 Clemson Tigers football team was an American football team that represented Clemson College in the Southern Conference during the 1949 college football season. In its tenth season under head coach Frank Howard, the team compiled a 4–4–2 record (2–2 against conference opponents), tied for seventh place in the Southern Conference, and outscored opponents by a total of 232 to 216. The team played its home games at Memorial Stadium in Clemson, South Carolina.