The 1949 Oklahoma Sooners football team represented the University of Oklahoma in the 1949 college football season. In their third year under head coach Bud Wilkinson, the Sooners compiled an undefeated 11–0 record (5–0 against conference opponents), won the Big Six Conference championship, were ranked #2 in the final AP Poll, and outscored their opponents by a combined total of 399 to 88.