The 1978 Clemson Tigers football team was an American football team that represented Clemson University in the Atlantic Coast Conference (ACC) during the 1978 NCAA Division I-A football season. In its second season under head coach Charley Pell, the team compiled an 11–1 record (6–0 against conference opponents), won the ACC championship, defeated Ohio State in the 1978 Gator Bowl, was ranked No. 6 in the final AP and Coaches Polls, and outscored opponents by a total of 368 to 131. The team played its home games at Memorial Stadium in Clemson, South Carolina.