The 1981 Oregon Ducks football team represented the University of Oregon in the 1981 NCAA Division I-A football season. Playing as a member of the Pacific-10 Conference (Pac-10), the team was led by head coach Rich Brooks, in his fifth year, and played their home games at Autzen Stadium in Eugene, Oregon. They finished the season with a record of two wins and nine losses (2–9 overall, 1–6 in the Pac-10, ninth).