The 1999 NCAA Division II women's basketball tournament was the 18th annual tournament hosted by the NCAA to determine the national champion of Division II women's collegiate basketball in the United States. Two-time defending champions North Dakota defeated Arkansas Tech in the championship game, 80–63, to claim the Fighting Sioux's third consecutive and third overall NCAA Division II national title. The championship rounds were contested in Pine Bluff, Arkansas. Three teams made their first appearances in the NCAA Division II tournament: Binghamton, Lander, and Western Washington.