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About: 2,5-Dimethoxy-4-iodoamphetamine     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : umbel-rc:ChemicalSubstanceType, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substanceChemical compoundyago:WikicatAmphetaminesyago:Agent114778436yago:Amphetamine102704153yago:CausalAgent100007347yago:DesignerDrug103179489yago:Drug103247620yago:DrugOfAbuse103248958yago:Hallucinogen103479647yago:Inhibitor114724436yago:Matter100020827yago:PhysicalEntity100001930yago:PsychoactiveDrug104017137chemical compounddrugyago:Stimulant104320126yago:Substance100020090yago:WikicatDesignerDrugsyago:WikicatPsychedelicDrugsyago:WikicatTNFInhibitorsumbel-rc:ChemicalSubstanceType New Facet based on Instances of this Class

2,5-Dimethoxy-4-iodoamphetamine (DOI) is a psychedelic drug and a substituted amphetamine. Unlike many other substituted amphetamines, however, it is not primarily a stimulant. DOI has a stereocenter and R-(−)-DOI is the more active stereoisomer. In neuroscience research, [125I]-R-(−)-DOI is used as a radioligand and indicator of the presence of 5-HT2A serotonin receptors. DOI's effects have been compared to LSD, although there are differences that experienced users can distinguish. Besides the longer duration, the trip tends to be more energetic than an LSD trip, with more body load and a different subjective visual experience. The after effects include residual stimulation and difficulty sleeping, which, depending on the dose, may persist for days. While rare, it is sometimes sold as a s